Designs for Health B-Supreme, 60 vcaps

This powerful and effective B vitamin combination formula supplies B vitamins in their preferred coenzymated forms, where possible, so the body does not have to phosphorylate them in order to be used in biochemical reactions. Choline and TMG are included to help support efficient methylation for optimal genetic expression.1

HISTORY OF B VITAMINS

B vitamins are a family of water-soluble nutrients that were discovered together at the beginning of the 20th century, initially thought simply to be “vitamin B.” As nutrition advanced, however, it was learned that they are in fact a family of compounds, each with a distinct role to play in promoting health. B vitamins are now known to play critical roles in modu- lating biochemistry and metabolism, and represent the most common vitamins utilized by the body as cofactors for facilitating enzymatic function. The modern refined diet, high in sugar, alcohol, and devitalized foods, leads to lower levels of B vitamins. Numerous medications and chronic stress may lower B vitamin levels. High-risk populations such as vegans or vegetarians, alcoholics, the elderly, patients with congestive heart failure, or those who have had bariatric surgeries are at risk for vitamin B deficiencies.2,7 While B vitamins have mainly been researched individually, they also have efficacious power when taken together. For example, B-complex supplementation has been shown to decrease the levels of homocysteine, an inflammatory marker in cardiovascular, metabolic and neurological diseases, such as diabetic nephropathy and Alzheimer’s disease, slowing the rate of cognitive decline. B vitamins also exhibit analgesic effects via activating the nitric oxide GMPc pathway.